Carbylamine Reaction (Isocyanide Test) (R-NH₂ + CHCl₃ + 3KOH → R-NC (isocyanide) + 3KCl + 3H₂O)
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R-NH₂ + CHCl₃ + 3KOH → R-NC (isocyanide) + 3KCl + 3H₂O
What each symbol means
| Symbol | What it stands for |
|---|---|
| KOH | Strong base (alcoholic) |
| R-NC | Isocyanide (carbylamine) — foul smelling |
| CHCl₃ | Chloroform |
| R-NH₂ | Primary amine (1° only) |
When to use this
Test for primary amines only. The foul smell of isocyanide is diagnostic. Secondary and tertiary amines do not respond. Also known as isocyanide test.